Dehp full form
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If you have any questions, comments, or concerns about the content of this page, please contact us. Di 2-ethylhexyl phthalate DEHP. DEHP is on the Proposition 65 list because it can cause cancer and birth defects or other reproductive harm. Exposure to DEHP may increase the risk of cancer, and may also harm the male reproductive system. Exposure to DEHP during pregnancy may affect the development of the child. Proposition 65 requires businesses to determine if they must provide a warning about exposure to listed chemicals. What is DEHP?
Dehp full form
Di 2-ethylhexyl phthalate DEHP is a man-made chemical. It is a colorless liquid with a slight odor. DEHP is found throughout the environment at low levels. It gets into the environment mostly through the disposal of plastic waste in landfills. Most DEHP in the environment is found in sediments and soil. It sticks strongly to soil and breaks down slowly when it is near the surface. Indoors, DEHP can also stick to dust particles. DEHP stuck to particles in the air can return to the ground or bodies of water via rain or snow. DEHP does not usually evaporate into the air or easily dissolve in water. It can build up in fish and other water-dwelling species. DEHP is found in many plastic products.
Manufacturers of flexible PVC articles can choose among several alternative plasticizers offering similar technical properties as DEHP.
DEHP is the most common member of the class of phthalates , which are used as plasticizers. It is the diester of phthalic acid and the branched-chain 2-ethylhexanol. This colorless viscous liquid is soluble in oil, but not in water. Di 2-ethylhexyl phthalate is produced commercially by the reaction of excess 2-ethylhexanol with phthalic anhydride in the presence of an acid catalyst such as sulfuric acid or para -toluenesulfonic acid. It was first produced in commercial quantities in Japan circa and in the United States in DEHP has two stereocenters, [8] located at the carbon atoms carrying the ethyl groups.
DEHP is the most common member of the class of phthalates , which are used as plasticizers. It is the diester of phthalic acid and the branched-chain 2-ethylhexanol. This colorless viscous liquid is soluble in oil, but not in water. Di 2-ethylhexyl phthalate is produced commercially by the reaction of excess 2-ethylhexanol with phthalic anhydride in the presence of an acid catalyst such as sulfuric acid or para -toluenesulfonic acid. It was first produced in commercial quantities in Japan circa and in the United States in DEHP has two stereocenters, [8] located at the carbon atoms carrying the ethyl groups.
Dehp full form
Federal government websites often end in. The site is secure. Diethylhexyl phthalate DEHP is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. Due to the overuse of DEHP in many products, it enters and pollutes the environment through release from industrial settings and plastic waste disposal sites.
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Microscopic observations revealed a decrease in glycogen stores, a periportal accumulation of fat, and an accumulation of lipofuscin granules [ 77 ]. Absalan F. Wipe up dust regularly, using a damp cloth. The authors analyzed the concentration of DEHP and other common chemicals such as PCBs in testes from dogs from five different world regions. Fatty foods that are packaged in plastics that contain DEHP are more likely to have higher concentrations such as milk products, fish or seafood, and oils. About Governor Lt. The above two conditions can occur from either direct exposure of fetal testis or indirect maternal exposure. Functional disturbances of ovaries can cause many reproductive problems such as anovulation, irregular estrogen secretion, and sterility [ 44 ]. DEHP affects follicle growth through a reduction of E2 levels in vitro [ 46 ]. DEHP is reported to be nephrotoxic in mice, and DEHP may exacerbate this pathological change and lead to chronic progressive nephropathy. Possible role of phthalate in the pathogenesis of endometriosis: In vitro, animal, and human data. Food Additives and Contaminants. Adult animals that ate DEHP showed decreased fertility, damage to the testes, and liver and kidney damage. Abstract Diethylhexyl phthalate DEHP is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products.
Context - Diethylhexyl-phthalate DEHP is a substance that is mainly used as an additive in plastics to make them more flexible.
Hypotension and cardiac arrest in rats after infusion of mono 2-ethylhexyl phthalate MEHP , a contaminant of stored blood. DEHP can enter the body through inhalation, ingestion, and dermal contact on a daily basis, which has raised some concerns about its safety and its potential effects on human health. Archived from the original PDF on Contrasting hepatocytic peroxisome proliferation, lipofuscin accumulation and cell turnover for the hepatocarcinogens wy, and clofibric acid. Increased plasma levels of phthalate esters in women with advanced-stage endometriosis: A prospective case-control study. Brain-derived neurotrophic factor BDNF is a protein that plays a critical role in the survival of existing neurons and promotes the enhancement and differentiation of new neurons and their synapses [ 73 ]. MEHP is suspected to have an obesogenic effect. IDLH Immediate danger. Toxicological Sciences. In other projects. European Council for Plasticisers and Intermediates. It is a colorless liquid with a slight odor. IARC monographs on the evaluation of carcinogenic risks to humans. Shelby M.
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