White tablet 377
If you are a consumer or patient please visit this version. Dosage and Administration 2. Warnings and Precautions 5. Tramadol hydrochloride tablets are an opioid agonist indicated in adults for the management of pain severe white tablet 377 to require an opioid analgesic and for which alternative treatments are inadequate 1.
The pill is an elliptical or oval-shaped, white-colored tablet with an imprint of "". It has been identified to contain tramadol hydrochloride in the strength of 50 mg. This tablet is manufactured by Sun Pharmaceutical Industries Ltd. The size of this tablet is 13 mm. It is only available as a prescription from the doctor. This medicine is known to belong to the narcotic analgesic drug class.
White tablet 377
Tramadol is a prescription medication used to treat moderate to moderately severe pain in adults. Tramadol belongs to a group of drugs called opioid analgesics, which work by blocking pain signals in the body. This medication comes in immediate release tablet and that can be taken up to 6 times a day, with or without food. Tramadol also comes in extended-release tablet and capsule forms and are taken once a day, with or without food. Do not chew, divide, or break tramadol extended-release forms. Swallow them whole. Common side effects of tramadol include nausea, constipation, dry mouth, and fatigue. Tramadol can also cause dizziness or drowsiness. Do not drive or operate heavy machinery until you know how tramadol affects you. CYP2D6 is a protein in your body that is involved in the elimination of tramadol and other drugs from your body. Some patients have more or less of this protein in their bodies, affecting how much of the drug gets eliminated. Levels of CYP2D6 can vary greatly between individuals, and those having less of this protein are known as "poor metabolizers.
Serious, life-threatening, or fatal asalia nazario depression has been reported with the use of opioids, even when used as recommended. Instruct patients to inform their healthcare provider if they are taking, or plan to take serotonergic medications [see Warnings and Precautions 5. Inform patients of the risk of life-threatening respiratory depression, white tablet 377 information that the risk is greatest when starting tramadol hydrochloride tablets or when the dosage is increased, and that it can occur even at recommended dosages, white tablet 377.
If you are a consumer or patient please visit this version. Tramadol hydrochloride tablet, USP is a centrally acting analgesic. Its structural formula is:. The molecular weight of tramadol hydrochloride, USP is Tramadol hydrochloride, USP is a white, bitter, crystalline and odorless powder. It is readily soluble in water and ethanol and has a pKa of 9. In addition, each tablet contains the following inactive ingredients: pregelatinized starch, lactose anhydrous, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, titanium dioxide.
Mary's Medical Park Pharmacy. Tramadol hydrochloride tablet, USP is a centrally acting analgesic. Its structural formula is:. The molecular weight of tramadol hydrochloride, USP is Tramadol hydrochloride, USP is a white, bitter, crystalline and odorless powder. It is readily soluble in water and ethanol and has a pKa of 9. In addition, each tablet contains the following inactive ingredients: pregelatinized starch, lactose anhydrous, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, titanium dioxide, hypromellose and polysorbate
White tablet 377
If you are a consumer or patient please visit this version. Dosage and Administration 2. Warnings and Precautions 5. Tramadol hydrochloride tablets are an opioid agonist indicated in adults for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate 1. Limitations of Use 1. Because of the risks of addiction, abuse, and misuse with opioids, which can occur at any dosage or duration, reserve tramadol hydrochloride tablets for use in patients for whom alternative treatment options [e. Life-Threatening Respiratory Depression. Serious, life-threatening, or fatal respiratory depression may occur with use of tramadol hydrochloride tablets, especially during initiation or following a dosage increase.
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In some reports, hyponatremia resulted from the syndrome of inappropriate antidiuretic hormone secretion SIADH. If an opioid analgesic is initiated in a patient already taking a benzodiazepine or other CNS depressant, prescribe a lower initial dose of the opioid analgesic, and titrate based on clinical response. Because strategies for the management of overdose are continually evolving, it is advisable to contact a poison control center where available to determine the latest recommendations for the management of an overdose. Tramadol 11 1. It is usually given after an individual has undergone surgery or an accident. The mean ratio of serum tramadol in the umbilical veins compared to maternal veins was 0. Risk of convulsions may also increase in patients with epilepsy, those with a history of seizures, or in patients with a recognized risk for seizure such as head trauma, metabolic disorders, alcohol and drug withdrawal, CNS infections. Drug Label Info. Avoid the use of tramadol hydrochloride tablets in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of tramadol unless the benefits outweigh the risks. Simple Facebook login.
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If concomitant treatment of tramadol hydrochloride tablet with a drug affecting the serotonergic neurotransmitter system is clinically warranted, careful observation of the patient is advised, particularly during treatment initiation and dose increases see WARNINGS, Serotonin Syndrome. Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. In a randomized, blinded clinical study with to patients per group, a day titration to a daily tramadol hydrochloride dose of mg 50 mg four times per day , attained in 50 mg increments every 3 days, was found to result in fewer discontinuations due to dizziness or vertigo than titration over only 4 days or no titration. Tramadol should not be given to a child younger than 12 years old, or anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids. The concomitant use of opioids with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. In studies including geriatric patients, treatment-limiting adverse events were higher in subjects over 75 years of age compared to those under 65 years of age. Warnings and Precautions 5. In patients taking opioids for an extended period of time at high doses, ensure that a multimodal approach to pain management, including mental health support if needed , is in place prior to initiating an opioid analgesic taper [ see Dosage and Administration 2. Intervention: Frequently reevaluate the prothrombin time of patients on warfarin for signs of an interaction and adjust the dosage of warfarin as needed. If concomitant use is warranted, frequently evaluate the patient, particularly during treatment initiation and dose adjustment. Consider prescribing naloxone for the emergency treatment of opioid overdose [see Dosage and Administration 2. The mean ratio of serum tramadol in the umbilical veins compared to maternal veins was 0.
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