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Tramadol is a prescription medication used to treat moderate to moderately severe pain in adults.

If you are a consumer or patient please visit this version. Dosage and Administration 2. Warnings and Precautions 5. Tramadol hydrochloride tablets are an opioid agonist indicated in adults for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate 1. Limitations of Use 1. Because of the risks of addiction, abuse, and misuse with opioids, which can occur at any dosage or duration, reserve tramadol hydrochloride tablets for use in patients for whom alternative treatment options [e. Life-Threatening Respiratory Depression.

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If one is not available, you can dispose of tramadol hydrochloride tablets by mixing the product with dirt, cat litter, or coffee grounds; placing the mixture in a sealed plastic bag, and throwing the bag in your trash. Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly. Using products containing alcohol white oval pill with 377 treatment with tramadol hydrochloride tablets may cause you to overdose and die.

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Tramadol hydrochloride is the active ingredient present in this pill. It is available in the form of a tablet and belongs to a category of drug called narcotic analgesics, which block the signals causing pain in any part of the body. Get to know how pill works, its side effects, precautions, and contraindications where pills is not suggested. The most common brand name is Ultram. When it is taken in combination with acetaminophen, then it starts working earlier than alone tramadol hydrochloride. It works by altering the way, all types of pain are perceived by the brain and body.

White oval pill with 377

The white elliptical pill with the imprint has been identified as Tramadol Hydrochloride 50 mg supplied by Sun Pharmaceutical Industries Inc.. The tramadol pill is a prescription drug and belongs to the drug class narcotic analgesics. This pill is a controlled substance.

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The maximum dosage is 1 or 2 tablets every 4 to 6 hours, as needed for pain relief. Clinical Presentation Acute overdosage with tramadol hydrochloride tablets can be manifested by respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, and, in some cases, pulmonary edema, bradycardia, QT prolongation, hypotension, partial or complete airway obstruction, atypical snoring, seizures, and death. When discontinuing tramadol hydrochloride tablets, gradually taper the dosage using a patient-specific plan that considers the following: the dose of tramadol hydrochloride tablets the patient has been taking, the duration of treatment, and the physical and psychological attributes of the patient. E m bryo-Fetal Toxicity Inform female patients of reproductive potential that tramadol hydrochloride tablets may cause fetal harm and to inform the healthcare provider of a known or suspected pregnancy [see Use in Specific Populations 8. Concomitant use of tramadol hydrochloride tablets increase the seizure risk in patients taking [see Drug Interactions 7 ] : Selective serotonin re-uptake inhibitors SSRI antidepressants or anorectics , Tricyclic antidepressants TCAs , and other tricyclic compounds e. After stopping a CYP3A4 inhibitor, as the effects of the inhibitor decline, the tramadol plasma concentration will decrease [see Clinical Pharmacology Acute overdosage with tramadol hydrochloride tablets can be manifested by respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, and, in some cases, pulmonary edema, bradycardia, QT prolongation, hypotension, partial or complete airway obstruction, atypical snoring, seizures, and death. Tramadol hydrochloride tablets can make you sleepy, dizzy, or lightheaded. Did you experience many side effects while taking this drug? Tramadol Cautionary Labels Back to Top. Hypotension Inform patients that tramadol hydrochloride tablets may cause orthostatic hypotension and syncope. In most cases, patients had predisposing risk factors e. Avoid the use of tramadol hydrochloride tablets in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of tramadol [see Warnings and Precautions 5. Tramadol causes a reduction in motility associated with an increase in smooth muscle tone in the antrum of the stomach and duodenum.

This medicine is known as quetiapine. Getting a good night's sleep is important for your physical and mental health.

Intervention: If concomitant use is necessary, consider dosage reduction of tramadol hydrochloride tablets until stable drug effects are achieved. Accidental ingestion of even one dose of tramadol hydrochloride tablets, especially by children, can result in a fatal overdose of tramadol [ see Warnings and Precautions 5. Opioids have been shown to have a variety of effects on components of the immune system in in vitro and animal models. Inform patients and caregivers not to increase opioid dosage without first consulting a clinician. Food Effects Oral administration of tramadol hydrochloride tablets with food does not significantly affect its rate or extent of absorption, therefore, tramadol hydrochloride tablets can be administered without regard to food. This medication comes in immediate release tablet and can be taken up to 6 times a day, with or without food. Cardiac arrest or serious arrhythmias will require advanced life-supporting measures. Tell your healthcare provider right away if you have some or all of the following symptoms of serotonin syndrome: hallucinations fast heart rate overactive reflexes high blood pressure restlessness or agitation nausea or vomiting decline in muscle coordination rise in body temperature discontinuation symptoms. Advise women that breastfeeding is not recommended during treatment with tramadol hydrochloride tablets [see Warnings and Precautions 5. Do not take more than your prescribed dose and do not take more than 8 tablets per day. Explain to patients and caregivers that naloxone's effects are temporary, and that they must call or get emergency medical help right away in all cases of known or suspected opioid overdose, even if naloxone is administered [see Overdosage 10 ]. Preoccupation with achieving adequate pain relief can be appropriate behavior in a patient with inadequate pain control. To reduce the risk of respiratory depression, proper dosing and titration of tramadol hydrochloride tablets are essential [ see Warnings and Precautions 5.