Nip activity

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Nip activity

Federal government websites often end in. The site is secure. The non-specific normal immunosuppressive protein Nip has been described in our laboratory and its biological activity was extensively studied. In the present study, further purification analyses of Nip were conducted. Fractionation of Nip by Ultrogel AcA 34 column resulted in peak I that displayed Nip activity in that it exhibited marked inhibition of in-vitro blastogenic responses of human lymphocytes to mitogenic stimulation, in vitro it inhibited EL4 tumour-cell proliferation. Partial dissociation of Ultrogel peak I on sodium dodecyl sulphate polyacrylamide gel electrophoresis SDS-PAGE resulted chiefly in three bands: one of high molecular weight, which is considered to be the carrier, an intermediate band of 50,, under non-reducing conditions and a band of high mobility and low molecular weight approximately 6,, The biological activity resided in the second peak, which corresponded to the low molecular weight fraction of 6,, Nip is suggested to be a complex molecule comprised of a low molecular weight peptide or glycopeptide, which displays the biological activity, and a macromolecular glycoprotein carrier, which conserves its stability. Full text is available as a scanned copy of the original print version. Get a printable copy PDF file of the complete article 2. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article.

Abstract The non-specific normal immunosuppressive protein Nip has been described in our laboratory and its biological activity was extensively studied. We've teamed up with reputable asset recovery companies to address your situation, nip activity.

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Nip activity

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