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Breast cancer is the most common cancer in women. The main organs in which BC metastasises are the bones, lungs, liver, and brain. Researchers are therefore seeking biomarkers for diagnosis and metastasis in different organs. Optimally, such biomarkers should be easy to detect using, preferably, non-invasive methods, such as using miRNA molecules, which are small molecules of about 22 nt that have as their main function the post-transcriptional regulation of genes. Furthermore, due to their uncomplicated detection and reproducibility in the laboratory, they are a tool of complementary interest for diagnosis, prognosis, and treatment. With this in mind, in this review, we focus on describing the most current studies that propose using miRNA independently as a potential biomarker for the diagnosis and prediction of brain, lung, liver, and bone metastases, as well as to open a window of opportunity to deepen this area of study to eventually use miRNAs molecules in clinical practice for the benefit of BC patients. Keywords: breast cancer subtypes; diagnostic; metastasis; microRNA.

Mirna silva

Federal government websites often end in. The site is secure. Individual raw data is available from the corresponding author upon reasonable request. In this study we compared six commercial RNA extraction kits to evaluate their ability to isolate miRNA from ovine plasma. We also compared three methods for quantification of small RNA extracted from plasma to determine the most reliable. Using minimal sample inputs of fresh and frozen plasma from five sheep, we compared the six kits Kit A-F using quantitative PCR. Operational factors were also assessed for each kit. We identify Kit A to be optimal for isolating miRNA from small volumes of fresh and frozen ovine plasma, and Kit B the top performing kit taking into consideration miRNA detection and operational factors. At the forefront of disease research in both human and veterinary medicine, predictive and diagnostic biomarkers have the potential to be highly specific and informative. Biofluids such as plasma, serum, saliva, or urine are common targets for biomarker profiling as they are collected by minimally invasive techniques and contain biologically relevant molecules which may be indicative of disease outcomes 1.

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Includes Address 4 Phone 3 Email 4. Includes Address 2. Includes Address 8 Phone 4 Email 1. Please make your own determination of the relevance of these court records. Includes Address 6 Phone 9. Lived In Philadelphia PA. Also known as Mirna L Hernandez. Includes Address 7 Phone 4. Also known as Mirna G Cabrera. The records below may not pertain to the individual that you're looking for, and may or may not pertain to the same charge. Disclaimer: By using this website, you accept the Spokeo Terms of Use.

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Also known as Mirna G Cabrera. Includes Address 1. Includes Address 1 Phone 1. Includes Address 4 Phone 8 Email 2. Includes Address 2 Phone 4 Email 1. Also known as Myrna Silva. Also known as Mirna E Vasquez. Please make your own determination of the relevance of these court records. Includes Address 11 Phone 4 Email 2. Lived In Lancaster CA. Includes Address 7 Phone 4. This site should not be used to make decisions about employment, tenant screening, or any purpose covered by the FCRA. Includes Address 4 Phone 3 Email 4. Browse Locations.